Complications oculaires de l’Imatinib.

cousineg · dim. févr. 01, 2009 4:14 am

Complications oculaires de l’Imatinib.
http://www.france-hemato.net/rdp2.php?num=4308

Merci Serge de nous avoir alerté de ce problème. Mon optométriste avait justement noté des saignements dans mes yeux. Je vais apporté cet artice à mon optométriste pour qu'il le mette dans mon dossier

cousineg · sam. août 01, 2009 4:18 pm

Voir aussi
Les désordres hématologiques et les yeux
http://www.alte-smp.org/forumalte3/view ... ?f=9&t=627

cousineg · dim. oct. 11, 2009 6:03 pm

« J’ai remarqué que le contour de mes yeux est enflé. Que puis-je faire ? », Revue Source. Septembre 2009
http://www.cmlsource.ca/noticed.php?lang=2

cousineg · lun. avr. 05, 2010 4:41 pm

Optic disc edema as a possible complication of Imatinib mesylate (Gleevec).
Kwon SI, Lee DH, Kim YJ.
Department of Ophthalmology, Hallym University Sacred Heart Hospital, Anyang,
Korea.
Ophthalmol. 2008 Jul-Aug;52(4):331-3. Epub 2008 Sep 5.

''BACKGROUND: Imatinib is effective for a variety of hematologic and
nonhematologic malignancies. Well-known ocular side effects are periorbital
edema, epiphora, extraocular muscle palsy, and blepharoconjunctivitis. However,
optic disc edema has not been reported as a complication of imatinib mesylate.
Herein, we describe a patient with chronic myeloid leukemia (CML) who developed
optic disc edema during treatment with imatinib. CASE: A 14-year-old Korean girl
was referred to ophthalmology for a 3-week history of photopsia in both eyes.
She had started taking imatinib daily 2 months previously for CML. At the
initial exam, slit lamp showed optic disc edema in both eyes, even though visual
acuity was 20/20 and other optic nerve function evaluations were within normal
limits. We recommended to the oncologist discontinuation of the imatinib
treatment.
OBSERVATIONS: When the patient was followed for 1 week after stopping
imatinib treatment, the frequency of photopsia decreased and the optic disc
edema improved. Because a second examination 3 weeks after discontinuation of
imatinib revealed much improved optic disc edema, she restarted the imatinib
treatment. No ocular side effects have been noted so far. CONCLUSIONS: Optic
disc edema should be considered one of the complications associated with
imatinib. We propose discontinuation of the treatment for a short period when
optic disc edema occurs.''
Extrait de http://www.springerlink.com/content/481708u25431r107/
Extrait de http://www.ncbi.nlm.nih.gov/pubmed/18773274

cousineg · dim. sept. 16, 2012 6:21 am

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