Les cykotines et la LMC

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Qu’est ce que les cykotines?
'Les cytokines sont impliquées dans le développement et la régulation du système immunitaire. Ce sont également des substances employées pour stimuler la formation des cellules sanguines (érythropoïèse) dans la moelle osseuse, où naissent les précurseurs des cellules adultes (" bébés" globules blancs et globules rouges).'
Extrait de http://www.vulgaris-medical.com/encyclo ... -1336.html


Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy
‘We therefore plan to expand our current CIK trial to include CML as a disease, for CML patients with various degree of response to the kinase inhibitors which have already offered its maximal effect. We aim to study whether autologous CIK cells may further improve disease response, either in the eradiation of minimal residual disease, or in conjunction with chemotherapy for control of high tumour load disease.’
Extrait de http://clinicaltrials.gov/ct2/show/NCT00815321

Cytokine-induced NK-like T cells: from bench to bedside
‘...chronic myeloid leukemia (CML) colony growth was reported to be suppressed by CIK cells and after 28 days of co-incubation, the remaining colonies in culture were exclusively composed of Philadelphia (Ph)-negative cells (22;23). Previously, we have shown that CIK cells could be generated from the marrow or peripheral blood samples from acute leukemia patients collected at diagnosis.’
Extrait de
http://downloads.mts.hindawi.com/MTS-Fi ... ZNQ1qGc%3D


Thomas' hematopoietic cell transplantation
Voir http://books.google.ca/books?id=e05V8L9 ... ml&f=false